The ABC’s of Cleaning Validation: A Simple Primer
What is Cleaning Validation? Cleaning validation is used to ensure that a cleaning procedure removes all trace soils, cutting fluids, fingerprints, particulates and cleaning agents from surfaces in regulated processes. Any residue must be removed to a predetermined level of cleanliness. Cleaning validation processes protect against the cross-contamination of ingredients from one batch to another,… [Read More]
Guidelines For Cleaning Pharmaceutical Processing Equipment
Cleaning pharmaceutical processing equipment is challenging. Cleaning methods, soils present, type of manufacturing equipment, surfaces cleaned, choice of cleaning detergent and temperature should all be considered when setting up a cleaning procedure. Cleaning validation methods are required. The entire cleaning process must be standardized and documented according to the FDA’s cGMP regulations. Why Clean Pharmaceutical… [Read More]
An Easy Guide to Understanding Surfactants
What is a Surfactant? Surfactants are a primary component of cleaning detergents. The word surfactant means surface active agent. As the name implies, surfactants stir up activity on the surface you are cleaning to help trap dirt and remove it from the surface. Surfactants have a hydrophobic (water-hating) tail and a hydrophilic (water-loving) head. The… [Read More]
Save Time And Money With Preventative Maintenance
It’s summer! It’s time to relax and enjoy the warmer weather. Kids are out of school, daylight hours are long, families flock to beaches and it seems like just about everyone takes a vacation. While summer means various things to different people, for many manufacturers summer means factory shutdowns, plant retooling and scheduled maintenance operations. What… [Read More]
How to Properly Clean Medical Devices
When it comes to medical devices cleanliness is crucial. All medical devices, whether they are disposable, implantable or reusable, must be cleaned during the manufacturing process to remove oil, grease, fingerprints and other manufacturing soils. Reusable products must also be thoroughly cleaned and sterilized between each use to avoid infecting patients or causing illness. Reaching… [Read More]
How do I Choose the Best Detergent for My Cleaning Application?
It’s easy to see that you have a dirty surface that needs to be cleaned. Figuring out what type of cleaner to use can be tricky! Choosing the right product from the outset will make your cleaning task easier, quicker and more efficient. So, how do you know which detergent to use? Dirt is Dirt,… [Read More]
Get The Most Out Of Your Cleaner…Know When To Add More
5 Ways To Know When To Change Your Cleaning Solution Choosing the best cleaner for your critical cleaning application takes time and careful consideration. With so many choices out there it can be difficult to figure out which cleaner is the best choice for your specific needs. Factors to consider: • What is the surface… [Read More]
What is the Chemistry That Makes Detergents Work?
We all have dirty surfaces that need to be cleaned. We see the soil, reach for the detergent, clean the surface and then move on with whatever we were doing, pretty much taking the whole process for granted. Have you ever stopped to think about what happens when you clean a dirty surface? What kind… [Read More]
Deciphering Reach and RoHS…The Alphabet Soup of Safety Standards
There are many safety standards that apply to chemical products. As new standards and regulations emerge it can be difficult for those who buy and use chemical products to keep up-to-date with proper safety requirements. Many businesses use chemicals in their day to day operations for manufacturing and maintenance. Sometimes it may seem as though… [Read More]
How To Keep Your Tablet Press Clean
10 Easy Steps for Cleaning Your Tablet Press Nothing can slow production down like equipment that malfunctions or stops working altogether. Performing regular, preventative maintenance of equipment is essential and helps keep pharmaceutical tablet presses functioning efficiently and smoothly. Tablet presses that are not well maintained can cause a multitude of problems, creating defective products… [Read More]
